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re-uptake造句
1 We reviewed the evidence for the efficacy and acceptability of serotonin reuptake inhibitors compared with the tricyclic and related antidepressants by meta-analysis. 2 Many drugs interfere with the reuptake of a neurotransmitter from synapses. 3 Many antidepressants just slow down the reuptake of the neurotransmitter into the presynaptic terminal. 4 The other argument for prescribing serotonin reuptake inhibitors has been their reported lower toxicity in overdose compared with some antidepressants. 5 However, disagreement exists about the role of serotonin reuptake inhibitors in treating major depression. 6 Other drugs block the reuptake of acetylcholine from a synapse and at the junction between neurones and muscles. 7 The concept works on the same principle as selective serotonin re-uptake inhibitors (SSRIs),[www.] such as popular antidepressant Prozac. 8 Thus, serotonin has only a brief influence on the target neurons. Drugs that prevent this re-uptake, such as Prozac, are frequently used to treat patients with depression. 9 These genes code for enzymes involved in the metabolism of many drugs, including selective serotonin re-uptake inhibitors (SSRIs). 10 This invention relates to novel alkyl substituted piperazine derivatives useful as monoamine neurotransmitter re-uptake inhibitors.