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blood-brain barrier造句
1, The ultrastructure of neonatal blood-brain barrier in the caudatum was observed and no significant differences were found between new-born babies and fetuses. 2, AIM: To predict the blood-brain barrier penetration by polar molecular surface area and molecular volume. 3, The blood-brain barrier protects the brain from harmful chemicals but also makes it difficult for drugs to reach the target cells. 4, The body has lots of different barriers – blood-brain barrier, the skin, the lining of the gut , the placenta – and it may be that this mechanism works in some of these barriers. 5, Terbutaline crosses the placental barrier and blood-brain barrier of the fetus, which may lead to an autistic-spectrum disorder and other developmental disorders. 6, P-glycoprotein inhibitors can get drugs across the blood-brain barrier. It is of great importance to improve the blood concentration in brain and bioavailability of central nervous system drugs. 7, ConclusionCortical neurons, neuroglia cells, cytoskeleton and blood-brain barrier changed at early stage of reperfusion damage. 8, Quantitatively assay the NE by ELISA, the permeability of Horseradish peroxidase (HRP) through the blood-brain barrier, observe the structural changes by scanning and transmission electron microscopy. 9, This invention relates to a highly efficient artificial low-density lipoprotein (LDL) carrier system for the targeted delivery therapeutic agents across the blood-brain barrier (BBB). 10, The capillary endothelium and the astrocytic sheath form the blood-brain barrier. 11, Studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier where it affects the synthesis and activation of various proteins, such as neurotransmitters. 12, Ninety-five percent of the body's serotonin is made by the gut, but gut serotonin cannot enter the brain because it is barred by a membrane, the so-called blood-brain barrier. 13, Additionally, methods for the use, identification and production of an inhibitor that does not substantially cross the blood-brain barrier are also provided. 14, In order to increase the capabilities of drugs through the blood-brain barrier, II and III were designed by means of amino acid-specific carrier-mediated transport system. 15, CONCLUSION: The vasogenic brain edema induced by glioma cells may not be the result of hyperpermeability of blood-brain barrier to macromolecules in plasma. 16, Cyclooxygenase-2 (COX-2) and its metabolic products can be involved in the mechanism of the ischemic brain injury through destructing the vascular system, blood-brain barrier and the neuron. 17, Hooper, previous studies by his group and other researchers have shown that blood-brain barrier permeability is critical in the development of MS. 18, Conclusion Early contrast- enhanced MRI is sensitive to reflect damage of blood-brain barrier, helping to predict ensuing hemorrhage. 19, Some of these molecules, such as leptin, have been shown in animal studies to cross the blood-brain barrier, suggesting a mechanism by which extra weight around the belly could be affecting the brain. 20, OBJECTIVE This paper studied the auxo-action of Borneol in the penetration of cisplatin(DDP) to the blood-brain barrier(BBB). 21, This article summarized several protein domains that can delivery drugs by passing blood-brain barrier and cell membrane barrier. 22, Objectives To explore morphologic changes of lesion interstitial laser thermotherapy induced and modification of the blood-brain barrier ( BBB) in the periphery of the lesion. 23, Objective To observe the expression of glucose transporter 1 (GLUT1) in the blood-brain barrier around the hematoma in rats with cerebral hemorrhage. 24, AIM: To investigate the effects of glioma cells on aquaporin expression in blood-brain barrier and their importance in pathophysiology. 25, Objective To study the influence of microwave radiation on the structure and function of blood-brain barrier in rats. 26, Of 18 patients with multiple sclerosis, there were 7 patients displayed oligoclonal band and 2 patients presented blood-brain barrier impairment. 27, Conclusion: EB may protect the brain from ischemia-reperfusion injury by increasing the activity of antioxidase, improving the cerebral blood flow, and alleviating the damage of blood-brain barrier.