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vioxx造句
1. Vioxx was taken off the market in 2004. 2. Safe natural alternative to Vioxx "and" Celebrex. 3. The recent Vioxx debacle bears this out. 4. The painkiller Vioxx was voluntarily withdrawn in 2004, and more recently the diabetes drug Avandia, which is still on the market, has been the focus of congressional inquiries and lawsuits. 5. Compared to placebos, Vioxx and Prexige were associated with twice the risk of heart attack. 6. Then in 2004, Merck withdrew its painkiller Vioxx after studies showed the pill increased the risk of heart attacks and strokes. 7. The findings also support prior research linking rofecoxib (Vioxx) with adverse cardiovascular effects. 8. After Vioxx and other safety controversies, "the American people no longer trust the FDA to protect their health, " said Nissen, who has served on FDA advisory panels. 9. Merck failed to warn doctors about the risks of its painkiller Vioxx. 10. Critics said the FDA should have reacted sooner to signs of problems related to Vioxx and other medicines on the market. 11. Investors are also suing Merck, saying it played down the risks of Vioxx and cost them billions of dollars in stock value after the drug was removed from the market. 12. The New Jersey-based drugmaker was sued by tens of thousands of former Vioxx users who claimed to have been injured by the arthritis medicine. 13. Celebrex, in the same class of medicines as Merck's recalled Vioxx, is Pfizer's third-best-selling drug. 14. The criminal charge arose out of the fact that Vioxx had also been promoted as a treatment for rheumatoid arthritis before being officially approved. 15. The increased cardiovascular risk compared with placebo was reported in a 2004 analysis of the adenomatous polyp prevention on Vioxx (APPROVe) study, w13 which led to the drug's withdrawal. 16. The drug maker also said the journal article contained "numerous inaccuracies" and that its conclusions were based on a limited selection of documents produced in the Vioxx litigation. 17. In April, the FDA rejected Merck's Arcoxia, anarthritis painkiller in the same drug class as Vioxx, eventhough it is widely available overseas. 18. In addition, researchers looked at the relative cardiovascular risks associated with three other drugs not sold in the U. S. , including Vioxx, Arcoxia, and Prexige. 19. On Sept. 30, 2004, pharmaceutical giant Merck announced it would voluntarily recall its worldwide stock of Vioxx, an arthritis drug that had brought in $2.5 billion in sales the previous year. 20. Merck is now likely to face a host of legal actions over Vioxx, including personal injury lawsuits from the victims of cardiac problems, or their relatives. 21. As a result, a jury recently returned a $253 million verdict against the company for the death of a patient who had been taking Vioxx. And this was only the first of many lawsuits.