kinase造句121. Objective To study the effects of high glucose on activity of mitogen activated protein kinase (MAPK) in cultured human mesangial cells and to explain the mechanism of diabetic nephropathy.
122. This is the first, and, to date, only trial of an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor to show a survival advantage for patients with advanced non-small cell lung cancer.
123. Method The activity of tyrosine protein kinase(TPK) was determined by using exogenic substrates in 16 samples of normal skin, 22 psoriatic lesion and 5 skin squamous carcinoma.
124. AIM To study the effects and kinetics of sodium quercetin 7 sulphate (SQMS) on recombinant human protein kinase CK2 holoenzyme.
125. Recently, tit in has been to signal transduction through its kinase domain to sense mechanical load.
126. The abnormal activity of tyrosine protein kinase was the cause with endometrium abnormal growth.
127. Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.
128. AIM To investigate the effect of acute and chronic lead exposure on CA1 long term potentiation(LTP) and active extracellular signal regulated kinase 2(ERK2) of rat hippocampus.
129. The change of tyrosine phosphatase activity following the kinase reflects the real time regulation of phosphorylation and dephosphorylation.
130. Protein tyrosine kinase(PTK) inhibitor is one of the new targets of oncotherapy.
131. Sphingosine kinase (SPK) is a key enzyme catalyzing the formation of sphingosine 1 phosphate (S1P), which is a lipid messenger with strong angiogenic activity.
132. AIM: To observe the inhibitory effect of luteolin on recombinant human protein kinase CK2 holoenzyme and to confirm the inhibitory type by its enzyme kinetic analysis in vitro.
133. The results showed that exogenous ethylene could increase ethylene production by 420% and 73%, reduce the activity of NAD kinase by 20% and 40% and had no obvious effects on NADP phosphatase activity.
134. The content of water and MDA in myocardium and creatin kinase (CK) in the coronary effluent were measured.
135. Adenylate kinase(AK) is a phosphotransferase enzyme that catalyzes the interconversion of adenine nucleotides, and plays an important role in cellular energy homeostasis.
136. Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
137. This study was to search specific CK2 inhibitors in tumor cells through observation of the inhibitory effects of baicalein on recombinant human protein kinase CK2 holoenzyme and its kinetic.
138. D5 is homologous with M-CK gene (muscle creatine kinase) and located at Gallus gallus chromos 32 bye-PCR on NCBI.