proto-oncogene造句
1, These proto-oncogenes can apparently cause cancer when something happens to disrupt their normal activities.
2, Contrast with proto-oncogene and with tumor-suppressor gene.
3, Activating mutations in the RET proto-oncogene cause hereditary MTC, which provides a strong therapeutic rationale for targeting RET kinase activity.
4, Rearrangements and mutations involving the RET(Rearranged During Transfection) proto-oncogene have been implicated closely in the papillary thyroid carcinoma(PTC).
5, The proto-oncogene KIT, a tyrosine kinase that is inhibited by Gleevec, is overexpressed in a majority of GISTs.
6, Objective To study the difference of RET proto-oncogene mutation between Hirschsprung's disease (HD) and allied disorders of Hirschsprung's disease (ADHD).
7, Objective To detect the mutations of the RET proto-oncogene in a pedigree with multiple endocrine neoplasia 2A( MEN 2A) .
8, Proto-oncogene is activated and the loss of tumor suppressor genes,[http:///proto-oncogene.html] often with people's lifestyles and behavior of external factors.
9, Proto-oncogene --- A normal gene involved in some aspect of cell division or proliferation that may become activated by mutation or other mechanism to become an oncogene.
10, Conclusion: The mRNA overexpression of MET proto-oncogene is correlated with tumor differentiation in ESCC.
11, The KRAS proto-oncogene product lies downstream of EGFR, and the mutation frees the receptor from normal regulation in cell-growth control.
12, Pituitary tumor transforming gene 1 (PTTG1) is a proto-oncogene and plays roles in promoting tumorigenesis and metastasis.
13, Objective To explore the correlation between chromosome fragile site in peripheral blood lymphocytes and proto-oncogene expression rate in patients with hepatocellular carcinoma.
14, Heat Shock Proteins may contribute to cell cycle regulation by interacting with proto-oncogene products or tumor suppressor gene products.
15, Initial mutation in a cancer cell, the activation of the normal cells in the proto-oncogene and their cancer had cancer cells.
16, Cyclin D1 is a key cell cycle regulator and a candidate proto-oncogene, whose deregulation has been implicated in pathogenesis of several types of cancers, including NPC.
17, The role of redox gene expression and alteration of proto-oncogene and anti-oncogene of cell exposed to arsenic in cell transformation has been studied.
18, Pancreatic carcinoma is a kind of malignant tumor of digestive system with badly prognosis. Its course of genesis results from the co-action of proto-oncogene, anti-oncogene and DNA repair gene.