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181. Nonreactivity may be related to fetal immaturity, a sleep cycle, drugs, fetal anomalies, or fetal hypoxemia. 182. Conclusions TRAIL and its receptor DR4 may be related to the immunologic process of corneal graft rejection, IL-1RA suppresses postoperative immunologic rejection in keratoplasty. 183. The mechanism might be related to reducing cholesterol, reducing blood mucosity, improving red cell transformation and reducing its aggregation to increase blood flow speed of vertebrobasilar artery.