最新研究表明,在肠沙门菌(Salmonella enterica)暴露前和暴露期间禁食, 可以保护小鼠不致发生完全感染,部分原因是由于动物肠道微生物群落的变化。当食物有限时,肠道微生物组似乎会隔离残留的营养物质,阻止病原体获得感染宿主所需的能量。
Fasting may help ward off infections, study in mice suggests
https://www.sciencedaily.com/releases/2021/08/210805140612.htm
Franziska A. Graef, Larissa S. Celiberto, Joannie M. Allaire, Mimi T. Y. Kuan, Else S. Bosman, Shauna M. Crowley, Hyungjun Yang, Justin H. Chan, Martin Stahl, Hongbing Yu, Candice Quin, Deanna L. Gibson, Elena F. Verdu, Kevan Jacobson, Bruce A. Vallance. Fasting increases microbiome-based colonization resistance and reduces host inflammatory responses during an enteric bacterial infection. PLOS Pathogens, 2021; 17 (8): e1009719 DOI: 10.1371/journal.ppat.1009719